The Combination of Mulberry Extracts and Silk Amino Acids Alleviated High Fat Diet-Induced Nonalcoholic Hepatic Steatosis by Improving Hepatic Insulin Signaling and Normalizing Gut Microbiome Dysbiosis in Rats

Figure 6

The profiles of gut microbiome by NGS analysis of gut microbial DNA. (a) The richness of gut microbiomes. (b) The fecal bacterial community by principal coordinate analysis (PCoA). (c) Proportion of taxonomic assignments [family] for gut microbiomes. Rats consumed high fat diets containing 0.2% (low dosage, -L) and 0.6% (high dosage, -H) of the mixture of mulberry extracts and silk amino acid (MS) and 0.6% cellulose (disease-control) for 12 weeks. MS1:3 and MS1:5 mixture contained 1:3 and 1:5 of mulberry extracts and silk amino acid, respectively. Bars with different letters were significantly different among the groups by Tukey test at P<0.05.

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