Antimalarial Activity of Cordia africana (Lam.) (Boraginaceae) Leaf Extracts and Solvent Fractions in Plasmodium berghei-Infected Mice

Figure 4

Effect of the 80% methanol crude leaf extract of C. africana on rectal temperature of P. berghei-infected mice in Rane’s test. Data are expressed as mean ± SEM; n = 6; a, compared to 10 ml/kg dH₂O; b, compared to CQ 25 mg/kg (positive control); c, compared to 200 mg/kg of the extract; d, compared to 400 mg/kg of the extract; e, compared to 600 mg/kg of the extract; ; ; ; CQ, chloroquine; CA, 80% methanol crude leaf extract of Cordia africana; dH₂O = distilled water.