Therapeutic Effects of Chinese Herbal Formula (PTQX) on NC/Nga Mice with Atopic Dermatitis-Like Skin Lesions

Figure 6

Treatment with PTQX inhibits the differentiation of T-helper 2 (Th2) and Th17 cells in the draining lymph nodes of NC/Nga mice with 1-chloro-2,4-dinitrobenzene- (DNCB-) induced atopic dermatitis. CD4+ Th1, Th2, Th17, and regulatory T (Treg) lymphocyte populations were selected by costaining for IFN-γ, IL-4, IL-17A, and Foxp3, respectively. Flow cytometry was used to evaluate these populations of lymphocytes in the spleens (a) and lymph nodes (b) of mice. A representative example of 2 replicate independent experiments is shown.

(a)

(b)