Research Article

Effects of Xuesaitong on the Pharmacokinetics of Losartan: An In Vivo UPLC-MS/MS Study

Table 2

Matrix effect and extraction recovery of losartan and EXP3174 in rat plasma (n = 6).

CompoundsConcentration (ng·mL−1)Matrix effect (%)RSD (%)Recovery (%)RSD (%)

Losartan592.438.6985.606.34
10093.254.04108.281.46
160096.821.34111.120.96
EXP31745101.986.2785.192.71
100115.747.75101.252.38
1600111.362.59109.792.51

RSD, relative standard deviation; RE, relative error.