Research Article
Effects of Xuesaitong on the Pharmacokinetics of Losartan: An In Vivo UPLC-MS/MS Study
Table 2
Matrix effect and extraction recovery of losartan and EXP3174 in rat plasma (n = 6).
| Compounds | Concentration (ng·mL−1) | Matrix effect (%) | RSD (%) | Recovery (%) | RSD (%) |
| Losartan | 5 | 92.43 | 8.69 | 85.60 | 6.34 | 100 | 93.25 | 4.04 | 108.28 | 1.46 | 1600 | 96.82 | 1.34 | 111.12 | 0.96 | EXP3174 | 5 | 101.98 | 6.27 | 85.19 | 2.71 | 100 | 115.74 | 7.75 | 101.25 | 2.38 | 1600 | 111.36 | 2.59 | 109.79 | 2.51 |
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RSD, relative standard deviation; RE, relative error.
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