Research Article

Cytotoxicity of Crude Extract and Isolated Constituents of the Dichrostachys cinerea Bark towards Multifactorial Drug-Resistant Cancer Cells

Figure 4

Effects of 6 h treatment of CCRF-CEM cells with crude extract and betulinic acid (1) on caspases activity. Samples were tested at their 1/2 × IC50, IC50 and 2 × IC50; IC50 values were 5.69 μg/mL for the crude extract and 8.80 μM for 1. Caspase activity is expressed as percentage (%) compared to untreated cells. Shown are mean±SD of three independent experiments.