Research Article

Effect of Xylocarpus granatum Bark Extract on Amelioration of Hyperglycaemia and Oxidative Stress Associated Complications in STZ-Induced Diabetic Mice

Table 3

Effect of X. granatum ethanol bark extracts on blood glucose level. Data are expressed as mean ± S.D. (n=5). Data in parentheses indicate % increase. NC, Control mice; NCT, Normal Control mice +Toxicological (high) dose Xylocarpus granatum; DMC, Diabetic Control mice; DMD, Diabetic mice+ Drug (Glibenclamide); DML, Diabetic mice + Xylocarpus granatum Low dose (100 mg/kg); DMH, Diabetic mice + Xylocarpus granatum High dose (200 mg/kg). p <0.05 compared with NC group. p<0.05 compared with DMC group.

GroupsBlood glucose level (mg/dl)
Day Day Day Day day

NC128.0 ± 6.32131.6 ± 5.54143.0 ± 9.13151.2 ± 9.65157.0 ± 9.77
NCT125.4 ± 2.96131.6 ± 3.91144.4 ±13.59149.0 ±14.86154.0 ±15.76
DMC311.4 ± 37.87346.2 ±30.93358.0 ±31.45380.6 ±37.36393.2 ±32.07
(+11.17%)(+14.96%)(+22.22%)(+26.26%)
DMD343.0 ± 56.43316.6 ±56.93285.6 ± 61.47257.4± 42.67232.8±38.17
(-7.69%)(-16.73%)(-24.95%)(-32.12%)
DML322.2 ± 67.76351.2 ± 72.59338.6 ± 55.87291.0 ± 61.15261.2 ± 67.08
(+9.0%)(+5.09%)(-9.68%)(-18.93%)
DMH324.0 ± 79.68335.2 ± 64.37308.4 ± 61.06268.2± 40.73218.4±36.42
(+3.45%)(-4.81%)(-17.22%)(-32.59%)