Acute and Subchronic Oral Toxicity of Fermented Green Tea with Aquilariae Lignum in Rodents
Table 2
Relative organ weights after a single oral dose of fGT.
Control (male/female)
fGT (male/female)
2.0 g/kg
1.0 g/kg
0.5 g/kg
Brain
1.45 ± 0.05/1.90 ± 0.16
1.45 ± 0.07/1.95 ± 0.11
1.45 ± 0.09/1.81 ± 0.09
1.42 ± 0.04/2.02 ± 0.11
Heart
0.49 ± 0.03/0.50 ± 0.03
0.47 ± 0.06/0.49 ± 0.04
0.47 ± 0.05/0.48 ± 0.05
0.46 ± 0.06/0.55 ± 0.06
Lymph node
0.02 ± 0.00/0.03 ± 0.01
0.02 ± 0.01/0.04 ± 0.02
0.03 ± 0.01/0.03 ± 0.01
0.03 ± 0.01/0.02 ± 0.01
Spleen
0.29 ± 0.05/0.40 ± 0.04
0.28 ± 0.05/0.36 ± 0.03
0.29 ± 0.04/0.43 ± 0.09
0.27 ± 0.05/0.38 ± 0.03
Thymus
0.13 ± 0.04/0.20 ± 0.07
0.15 ± 0.02/0.28 ± 0.08
0.15 ± 0.03/0.24 ± 0.05
0.13 ± 0.03/0.21 ± 0.03
Liver
4.39 ± 0.26/4.25 ± 0.23
4.24 ± 0.22/4.32 ± 0.18
4.51 ± 0.35/4.48 ± 0.29
4.15 ± 0.09/4.53 ± 0.20
Pancreas
0.52 ± 0.06/0.53 ± 0.05
0.54 ± 0.08/0.53 ± 0.05
0.53 ± 0.08/0.52 ± 0.03
0.55 ± 0.08/0.57 ± 0.03
Lung
0.51 ± 0.02/0.64 ± 0.03
0.52 ± 0.04/0.67 ± 0.05
0.52 ± 0.04/0.65 ± 0.03
0.51 ± 0.03/0.67 ± 0.03
Kidney
0.80 ± 0.08/0.67 ± 0.05
0.77 ± 0.09/0.64 ± 0.05
0.83 ± 0.15/0.63 ± 0.04
0.75 ± 0.08/0.70 ± 0.03
Adrenal gland
0.02 ± 0.01/0.02 ± 0.01
0.01 ± 0.01/0.02 ± 0.01
0.02 ± 0.01/0.02 ± 0.01
0.02 ± 0.01/0.02 ± 0.01
Testis
0.32 ± 0.02/—
0.31 ± 0.05/—
0.31 ± 0.06/—
0.32 ± 0.04/—
Epididymis
0.13 ± 0.02/—
0.13 ± 0.02/—
0.12 ± 0.01/—
0.12 ± 0.01/—
Ovary
—/0.13 ± 0.06
—/0.12 ± 0.04
—/0.09 ± 0.01
—/0.09 ± 0.04
Uterus
—/0.59 ± 0.22
—/0.56 ± 0.23
—/0.57 ± 0.31
—/0.76 ± 0.24
Mice (n = 5 per group each) were orally administered distilled water (Control) or fGT. The relative organ weight to the body weight (%) is expressed as mean ± standard deviation (SD).
