Adenine Inhibits the Growth of Colon Cancer Cells via AMP-Activated Protein Kinase Mediated Autophagy

Figure 3

Adenine-induced AMPK activation and regulated AMPK signaling. Colon cancer cells HT29 (a) and Caco-2 (b) were treated with a serial concentration of adenine for 24 h and then were lyzed for the measurements of protein levels of p-AMPK, AMPK, p-mTOR, and mTOR using western blotting.

(a)

(b)