Comparative Pharmacokinetic Study of Taxifolin after Oral Administration of Fructus Polygoni Orientalis Extract in Normal and Fibrotic Rats by UPLC-MS/MS

<table class="table-group" id="tab4"><tr><td><table class="table"><tr><td class="thead-hr" colspan="5"><hr/></td></tr><tr class="thead"><td class="align_left">Spiked concentration (ng/mL)</td><td class="align_center">Recovery (%)</td><td class="align_center">RSD (%)</td><td class="align_center">Matrix effect (%)</td><td class="align_center">RSD (%)</td></tr><tr><td class="thead-hr" colspan="5"><hr/></td></tr><tr><td class="align_left">50</td><td class="align_center">93.5</td><td class="align_center">5.1</td><td class="align_center">97.8</td><td class="align_center">6.6</td></tr><tr><td class="align_left">1000</td><td class="align_center">94.6</td><td class="align_center">4.5</td><td class="align_center">95.9</td><td class="align_center">5.6</td></tr><tr><td class="align_left">4000</td><td class="align_center">96.2</td><td class="align_center">2.4</td><td class="align_center">97.9</td><td class="align_center">3</td></tr><tr class="table-tr"><td colspan="5"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

<div>The mean recoveries and matrix of taxifolin and the internal standard in rat plasma (<i>n</i> = 6).</div>

Evidence-Based Complementary and Alternative Medicine

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Table 4

Table 4: Comparative Pharmacokinetic Study of Taxifolin after Oral Administration of Fructus Polygoni Orientalis Extract in Normal and Fibrotic Rats by UPLC-MS/MS 

Table 4 | Comparative Pharmacokinetic Study of Taxifolin after Oral Administration of Fructus Polygoni Orientalis Extract in Normal and Fibrotic Rats by UPLC-MS/MS 