In Vitro Antioxidant and In Vivo Lipid-Lowering Properties of Zingiber officinale Crude Aqueous Extract and Methanolic Fraction: A Follow-Up Study
Table 4
Changes of plasma HDL-C, LDL-C (mmol.l−1), and atherogenic index of plasma in control and treated mice.
4th week
8th week
12th week
HDL
LDL
AIP
HDL
LDL
AIP
HDL
LDL
AIP
NCG
1.41 ± 0.06
0.48 ± 0.08
0.49
1.45 ± 0.05
0.66 ± 0.07
0.62
1.43 ± 0.13
0.78 ± 0.04
0.76
HCG
1.02 ± 0,04
2.90 ± 0.13
2.79
0.88 ± 0.03
3.20 ± 0.11
3.43
0.91 ± 0.02
3.49 ± 0.14
4.46
AETG dose 1
1.36 ± 0.05
1.49 ± 0.05
1.42
1.43 ± 0.08
1.87 ± 0.04
1.64
1.45 ± 0.05
1.86 ± 0.10
1.62
AETG dose 2
1.42 ± 0.04
0.62 ± 0.06
0.66
1.49 ± 0.02
0.58 ± 0.09
0.62
1.55 ± 0.04
0.62 ± 0.08
0.65
STG
1.29 ± 0.03
0.53 ± 0.09
0.71
1.35 ± 0.06
0.59 ± 0.08
0.74
1.41± 0.06
0.56 ± 0.09
0.71
Values are expressed as means ± SEM from ten mice in each lot. TC: total cholesterol; TG: triglycerides; AI: atherogenic index. HCG compared with NCG. AETG and STG compared with HCG. a: p < 0.001; c: p < 0.05; b: p < 0.01; NS: not significant.
