Research Article

Toxicity Assessment of Chinese Herbal Medicine Cynomorium songaricum Rupr

Table 2

The results of the bacterial reverse mutation test.

ChemicalDose (μg/plate)Revertant colonies/plate
S9TA97TA98TAl00TAl02TA1535

Suo Yang8-113 ± 937 ± 8172 ± 21286 ± 1016 ± 2
40-120 ± 1340 ± 1172 ± 19289 ± 1310 ± 4
200-119 ± 1546 ± 4136 ± 12262 ± 1010 ± 8
1000-125 ± 1746 ± 2134 ± 5276 ± 713 ± 4
5000-121 ± 1539 ± 6151 ± 29256 ± 58 ± 3
Untreated control0-118 ± 1437 ± 7135 ± 18275 ± 1910 ± 3
Solvent control 10-111 ± 538 ± 8151 ± 14292 ± 311 ± 6
Solvent control 20-121 ± 1041 ± 4143 ± 15288 ± 1411 ± 5
Positive control 150-1723 ± 35818 ± 67786 ± 56
Positive control 21.5-1016 ± 90462 ± 23
Suo Yang8+121 ± 740 ± 1167 ± 25277 ± 2215 ± 3
40+114 ± 1137 ± 10151 ± 35272 ± 109 ± 4
200+127 ± 1441 ± 5158 ± 34273 ± 2116 ± 2
1000+123 ± 1239 ± 7165 ± 34263 ± 1913 ± 5
5000+120 ± 833 ± 4154 ± 27277 ± 2313 ± 7
Negative control0+126 ± 538 ± 10150 ± 13262 ± 1313 ± 3
Solvent control 10+124 ± 1936 ± 6177 ± 5279 ± 1411 ± 6
Solvent control 20+122 ± 637 ± 6148 ± 14287 ± 711 ± 6
Positive control 310+1533 ± 902141 ± 207921 ± 47
Positive control 450+796 ± 84
Positive control 5200+518 ± 19

Values are expressed as the means ± SD (n = 10).
Solvent control 1: sterile water; Solvent control 2: DMSO; Positive control 1: dimethylaminobenzene diazosulfonate sodium; Positive control 2: sodium azide; Positive control 3: 2-aminoanthracene; Positive control 4: 1,8-dihydroxyanthraquinone; Positive control 5: Endoxan.
P< 0.01 statistically significant compared to the untreated control group.