Modulation of Diacylglycerol-Induced Melanogenesis in Human Melanoma and Primary Melanocytes: Role of Stress Chaperone Mortalin
Effect of OAG and TXC on melanin and tyrosinase contents in human melanoma (G361) (a) and primary melanocytes from Caucasian skin (PMC) (b). Cells were treated with OAG for 24 h followed by recovery either in control (OAG) or TXC-supplemented medium as indicated. Melanosome (c) and tyrosinase (d) immunofluorescence signals in control and OAG-treated cells, recovered in either control, or TXC-supplemented medium are shown. (e) Quantitation of the immunofluorescence for melanosome and tyrosinase are shown.