Synergistic Effect of Network-Based Multicomponent Drugs: An Investigation on the Treatment of Non-Small-Cell Lung Cancer with Compound Liuju Formula
Effect of compound Liuju formula active component at the cellular level. (a, b) Cellular cytotoxicity assay. The x-axis shows the drugs concentrations. The y-axis shows the inhibition rate of drugs on cells. (c, d) Effect of apigenin, kaempferol, and ursolic acid on LPS-induced production of inflammatory mediators. Expression levels TNF-α and IL-1β in RAW264.7 cells: experience group cells treated with different dose medicines and analyzed by ELISA. A + K: apigenin and kaempferol; A + U: apigenin and ursolic acid; K + U: kaempferol and ursolic acid; A + K + U: apigenin, kaempferol, and ursolic acid. Data are presented as the mean ± SD (n = 3). ,, and .
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