Synergistic Effect of Network-Based Multicomponent Drugs: An Investigation on the Treatment of Non-Small-Cell Lung Cancer with Compound Liuju Formula

<div>Effect of compound Liuju formula active component at the cellular level. (a, b) Cellular cytotoxicity assay. The <i>x</i>-axis shows the drugs concentrations. The <i>y</i>-axis shows the inhibition rate of drugs on cells. (c, d) Effect of apigenin, kaempferol, and ursolic acid on LPS-induced production of inflammatory mediators. Expression levels TNF-<i>α</i> and IL-1<i>β</i> in RAW264.7 cells: experience group cells treated with different dose medicines and analyzed by ELISA. A + K: apigenin and kaempferol; A + U: apigenin and ursolic acid; K + U: kaempferol and ursolic acid; A + K + U: apigenin, kaempferol, and ursolic acid. 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Evidence-Based Complementary and Alternative Medicine

fig5

Figure 5

Figure 5: Synergistic Effect of Network-Based Multicomponent Drugs: An Investigation on the Treatment of Non-Small-Cell Lung Cancer with Compound Liuju Formula 

Figure 5 | Synergistic Effect of Network-Based Multicomponent Drugs: An Investigation on the Treatment of Non-Small-Cell Lung Cancer with Compound Liuju Formula 