Optimization Extraction of Shikonin Using Ultrasound-Assisted Response Surface Methodology and Antibacterial Studies

Table 4

Antibacterial activities of shikonin against G⁺ and G⁻ bacteria.

Strains	MIC (μg/mL)	MBC (μg/mL)
G^+
E. coli (ATCC 25922)	256	512
Salmonella (C79-13)	256	1024
P. Aeruginosa (ATCC 9027)	512	1024
E. coli isolates	512∼1024	1024∼2048
Salmonella isolates	128∼512	256∼1024
G^−
S. agalactiae (ATCC 13813)	128	256
S. Aureus (ATCC 25923)	128	256
S. aureus isolates	512∼1024	1024∼2048