Research Article

Antidepression and Prokinetic Effects of Paeoniflorin on Rats in the Forced Swimming Test via Polypharmacology

Table 1

Effects of paeoniflorin on plasma SOD and MDA of rats with FST ( ± SD).

GroupnSOD (U/ml)nMDA (nmol/l)

NC group9104.50 ± 7.57105.29 ± 0.75
M group1047.93 ± 8.981011.11 ± 0.78
F group963.21 ± 8.1796.38 ± 0.59
P group1074.33 ± 7.67107.48 ± 0.75
value0.0000.000

Data are shown as mean ± standard deviation ( ± SD), and one-way analysis of variance (ANOVA) followed by a least significant difference (LSD) test was used to evaluate the data. indicated a statistically significant difference. Compared with the NC group, ; compared with the M group, . SOD: superoxide dismutase; MDA: methane dicarboxylic aldehyde; FST: forced swimming test; NC: normal control; M: model; F: fluoxetine; P: paeoniflorin.