Combined Extracts of Epimedii Folium and Ligustri Lucidi Fructus with Budesonide Attenuate Airway Remodeling in the Asthmatic Rats by Regulating Apoptosis and Autophagy

Figure 1

Effects of bud and EEL on airway remodeling. The inflammatory cell infiltration and airway remodeling were observed by (a) the perimeter of basement membrane (Pbm), (b) the standardized thickness of airway wall (Wat), and (c) the standardized thickness of airway smooth muscle (Wam) in H&E-stained lung sections. The goblet cell hyperplasia was assessed by (d) the number of goblet cell and (e) the area of goblet cell in PAS-stained lung sections. (f) The area of collagen fiber in Masson’s trichrome-stained lung sections. (g) Representative photomicrographs of H&E-stained, PAS-stained, and Masson’s trichrome-stained lung sections from each group (×400). Data are represented as mean ± SD; n = 6. compared with control group; and compared with asthma group; compared with Bud group; compared with EEL group.

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