Research Article

Effect of Qing’e Decoction on Leptin/Leptin Receptor and Bone Metabolism in Naturally Aging Rats

Table 1

Correlation analysis of LEP, LEP-R, and bone metabolism markers.

BMDE2TOPGRANKLCbfa1Col-IOCBALPTRACP-5b

LEP0.136−0.480−0.170−0.405−0.442−0.407−0.330−0.198−0.095−0.058
LEP-R0.1320.7440.7380.8400.5400.7930.8080.2240.5800.242

Significant correlation at 0.01 level (bilateral), Significant correlation at 0.05 level (bilateral). BMD: bone mineral density, E2: estradiol, T: testosterone, OPG: osteoporogeterin, RANKL: receptor activator of nuclear factor-κ B ligand, Cbfa-1: core-binding factor subunit alpha-1,COL-1: collagen?, OC: osteocalcin, BALP: bone alkaline phosphotase, TRACP-5b: tartrate-resistant acid phosphatase 5b.