Evaluation of Antiulcer Activity of 80% Methanol Extract and Solvent Fractions of the Root of Croton macrostachyus Hocsht: Ex Del. (Euphorbiaceae) in Rodents

Figure 3

Effects of fractions of C. macrostachyus on the acidified ethanol-induced ulcer model in mice. a = NC, b = AF100, c = AF200, d = AF400, e = EF100, f = EF200, g = EF400, h = CF100, i = CF200, j = CF400, and k = SUC100. In this figure, some spot ulcers and many hemorrhagic strikes were obviously observed from the negative control (a) and almost in all doses of aqueous fractionate (b, c, d). On the other hand, as we go from ethyl acetate fractionate to chloroform fractionate (e, f, g and h, i, j; from lower to higher doses, respectively), the formation of different types of significant ulcers were not well-observed in advance.