Efficacy and Safety of Aidi Injection as an Adjuvant Therapy on Advanced Breast Cancer: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Table 3

Safety of ADI.

Outcomes	No. of trials	Heterogeneity		Effect size with 95% CI	Z with value
		Chi-squared	I-squared (%)
Hepatic function
AST	3^22,23,25	112.69 ()	98	−31.21 (−47.06∼−15.36)	3.86 ()
ALT	3^22,23,25	4.86 ()	59	−4.04 (−5.57∼−2.51)	5.16 ()
γ-GT	2^23,25	0.08 ()	0.0	−24.59 (−27.78∼−21.40)	15.1 ()
Cardiac function
CK-MB	2^22,23	0.64 ()	0.0	−4.04 (−5.91∼−2.17)	4.23 ()