Research Article

Fortified S-Allyl L-Cysteine: Animal Safety, Effect on Retinal Ischemia, and Role of Wnt in the Underlying Therapeutic Mechanism

Table 2

The effect on electroretinogram a-wave amplitudes (mV) changes after oral gavage for 4 weeks of preischemia daily doses of SAC or Vehicle treatment.

Time/groupVehicleSAC 0.18 mgSAC 0.018 mgSAC 0.0018 mg

Baseline0.08 ± 0.020.06 ± 0.020.09 ± 0.020.07 ± 0.02
Week 10.01 ± 0.030.09 ± 0.020.07 ± 0.020.05 ± 0.01
Week 20.09 ± 0.030.08 ± 0.020.10 ± 0.020.06 ± 0.02
Week 30.07 ± 0.020.07 ± 0.020.06 ± 0.020.06 ± 0.02
Week 40.09 ± 0.030.07 ± 0.020.09 ± 0.020.06 ± 0.01