Research Article

Anticancer Activity of Modified Tongyou Decoction on Eca109 Esophageal Cancer Cell Invasion and Metastasis through Regulation of the Epithelial-Mesenchymal Transition Mediated by the HIF-1α-Snail Axis

Table 4

Regrowth degree of Eca109 cell was affected by different factors (μm, ).

0 h24 h

Group OC661.44 ± 4.460.00 ± 0.00
Group OM669.37 ± 3.75478.59 ± 11.53
Group HC681.57 ± 5.880.00 ± 0.00
Group HM649.50 ± 9.87607.45 ± 6.90

Note: at 0 h time point, scratch width showed no statistical significance among 4 groups, one-way ANOVA. At 24 h time point, scratch width disappeared in Group OC and Group HC. In Group OM, scratch width was still present, showing statistical difference from that in Group OC,  < 0.05. In Group HM, scratch width was still present, showing statistical difference from that in Group HC,  < 0.05. Homogeneity of variance by one-way ANOVA; LSD test applied to indicate statistical difference