Research Article

Sini-San Regulates the NO-cGMP-PKG Pathway in the Spinal Dorsal Horn in a Modified Rat Model of Functional Dyspepsia

Table 2

Abdominal withdrawal reflex score of rats (mean ± SE, n = 6/group).

Group20 mm Hg40 mm Hg60 mm Hg80 mm Hg

Normal0.33 ± 0.211.00 ± 0.262.17 ± 0.31a3.17 ± 0.31a
Model0.33 ± 0.211.83 ± 0.31a3.33 ± 0.33a3.83 ± 0.17b
Low-dose SNS0.50 ± 0.221.17 ± 0.173.33 ± 0.21b3.82 ± 0.17b
Middle-dose SNS0.33 ± 0.211.00 ± 0.263.00 ± 0.26b3.17 ± 0.31a
High-dose SNS0.33 ± 0.211.00 ± 0.263.00 ± 0.26a3.50 ± 0.22b

, , vs. the distension of 20 mm Hg in the same group.