Effect of Aqueous Extract of Adansonia digitata Stem Bark on the Development of Hypertension in L-NAME-Induced Hypertensive Rat Model

Table 3

Effects of A. digitata extract on the electrocardiogram of hypertensive rats.

ECG Parameter	Time (ms)						Magnitude (mV)
	P-R Int	QRS Int	Q-T Int	S-T Int	S-T Seg	R-R Int	P wave	QRS complex
Normotensive ctrl	43.3 ± 0.3	22.0 ± 1.0	66.0 ± 3.9	35.0 ± 0.5	5.0 ± 0.1	148.3 ± 0.4	0.09 ± 0.01	0.58 ± 0.01
Hypertensive ctrl	42.7 ± 0.6	37.7 ± 0.6^c	85.7 ± 0.6^b	39.3 ± 0.3	8.7 ± 0.3	159.3 ± 0.3	0.08 ± 0.01	0.61 ± 0.01
LN + captopril	45.7 ± 0.3	19.7 ± 0.8^δ	62.0 ± 0.3^β	40.3 ± 1.2	7.0 ± 0.5	168.8 ± 0.6	0.08 ± 0.01	0.48 ± 0.02
LN + AD100	49.3 ± 0.6^α	30.3 ± 0.8	65.3 ± 1.0^β	40.3 ± 0.8	6.6 ± 0.3	169.7 ± 0.8	0.12 ± 0.01	0.73 ± 0.02
LN + AD200	49.3 ± 0.6^α	21.0 ± 0.0^δ	65.6 ± 1.5^β	46.0 ± 0.9	7.6 ± 0.3	156.0 ± 1.0	0.11 ± 0.01	0.43 ± 0.02

Data are mean ± SEM (N = 6 per group). ANOVA + the Tukey test: ^b vs. the normotensive control group; ^δ, ^β, and ^α vs. the hypertensive control group. AD100/AD200 = extract doses 100 or 200 mg/kg. Int = interval. LN = N-NAME. Seg = segment.