Research Article

YQFM Alleviates Side Effects Caused by Dasatinib through the ROCK/MLC Pathway in Mice

Figure 2

Effect of YQFM on Dasatinib-induced intestinal vascular leakage and contents of S-VE-cadherin and D-lactic acid. YQFM (0.336, 0.672, 1.342 g/kg, i.p.) was injected intraperitoneally 1 h before being administered with dasatinib (70 mg/kg for 3 d, i.p.). (a) Representative gross appearance of the EB-stained intestine of a mouse. Data are expressed as the mean ± SD, n = 6. vs. control group; vs. model group. (c) Content of S-VE-cadherin was analysed by ELISA. (d) Content of D-lactic acid was analysed by ELISA. Data are expressed as the mean ± SD. vs. control group; vs. model mice, vs. model group.
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