Cordia lutea L. Flowers: A Promising Medicinal Plant as Chemopreventive in Induced Prostate Carcinogenesis in Rats
Table 3
Biochemical parameters of experimental groups treated with Cordia lutea for 5 months.
Parameters
Control (NS)
Induced cancer
C. lutea 50 mg/kg
C. lutea 250 mg/kg
C. lutea 500 mg/kg
AST (IU/L)
164.19 ± 8.31
199.01 ± 7.76
184.43 ± 12.10
175.40 ± 7.55
173.50 ± 5.07
ALT (IU/L)
66.63 ± 3.46
88.57 ± 10.77
85.63 ± 7.40
81.10 ± 3.29
78.80 ± 12.39
Alkaline phosphatase (IU/L)
311.2 ± 11.15
330.73 ± 5.93
320.60 ± 17.17
318.67 ± 16.04
316.43 ± 9.68
Total bilirubin (mg/dL)
0.71 ± 0.07
0.79 ± 0.09
0.75 ± 0.05
0.73 ± 0.09
0.73 ± 0.05
Total protein (g/dL)
6.80 ± 0.14
7.18 ± 0.22
7.11 ± 0.24
7.08 ± 0.12
6.98 ± 0.19
Albumin (g/dL)
3.96 ± 0.12
4.09 ± 0.07
3.90 ± 0.06
3.88 ± 0.05
3.93 ± 0.11
Cholesterol (mg/dL)
74.33 ± 7.02
89.33 ± 7.77
88.87 ± 11.20
87.73 ± 9.40
85.80 ± 3.86
Triglycerides (mg/dL)
107.00 ± 7.94
133.33 ± 6.66
129.67 ± 5.51
127.67 ± 7.02
120.87 ± 8.95
HDL (mg/dL)
31.00 ± 1.73
29.00 ± 2.00
30.83 ± 3.68
30.67 ± 1.15
32.67 ± 2.08
LDL (mg/dL)
21.93 ± 7.31
33.67 ± 8.42
32.10 ± 12.18
31.53 ± 9.79
28.96 ± 6.94
Glucose (mg/dL)
99.67 ± 2.52
97.00 ± 5.29
101.33 ± 2.52
104.33 ± 7.37
100.67 ± 2.31
Urea (mg/dL)
35.77 ± 3.13
39.13 ± 2.68
38.87 ± 4.75
41.80 ± 4.61
38.17 ± 2.46
Creatinine (mg/dL)
0.77 ± 0.04
0.84 ± 0.06
0.83 ± 0.06
0.84 ± 0.05
0.80 ± 0.04
Values are mean ± SD (expressed as mean ± standard deviation), significance when compared with control . One-way ANOVA followed by Tukey’s test. NS: normal saline; AST: aspartate aminotransferase; ALT: alanine aminotransferase; HDL: high-density lipoprotein; and LDL: low-density lipoprotein.