Research Article

An In Vitro Study for Evaluating Permeability and Metabolism of Kurarinone

Table 2

PAMPA effective permeability (Pe) values for kurarinone and permeability markers.

CompoundPe × 10−6 (cm/s)
pH = 4pH = 7

Naproxen (high permeability marker)5.38 ± 1.365.76 ± 1.75
Furosemide (low permeability marker)0.06 ± 0.010.07 ± 0.02
Kurarinone3.87 ± 1.392.14 ± 0.82