Evaluation of the Antimalarial Activity of the Hydroalcoholic Extract of Leaf of Leonotis ocymifolia (Burm. f.) Iwarsson (Lamiaceae) against Plasmodium berghei in Mice

Table 4

Body weight and rectal temperature of P. berghei-infected Swiss albino group treated with hydroalcoholic extract of leaf of Leonotis ocymifolia in Rane’s test.

Treatment (mg/kg)	Body weight			Temperature
	Day 3	Day 7	Change (%)	Day 3	Day 7	Change (%)
CON	35.320.96	32.370.99	−8.39	37.150.09	32.880.66	−8.3
HA 200 mg/kg	33.191.14	31.491.73	−5.20	37.090.12	33.660.37	−6.1
HA 400 mg/kg	32.751.35	31.641.20	−3.26	37.140.12	34.770.31	−3.3
HA 800 mg/kg	30.740.68	29.330.74	−4.64	37.030.21	35.030.26	−3.1^a1
CQ25 mg/kg	32.010.88	32.260.76	0.91^a1	37.040.12	36.820.29	3.1^a3d3e2f1

Data are expressed as mean ± SEM (n = 8); ^acompared to negative control; ^bcompared to CQ 25 mg/kg; ^dcompared to 200 mg/kg; ^ecompared to 400 mg/kg; ^fcompared to 800 mg/kg:  < 0.05,  < 0.01, and  < 0.001; HA, hydroalcoholic; CON, negative control; CQ, chloroquine.