Evidence-Based Complementary and Alternative Medicine / 2020 / Article / Fig 6

Research Article

Tea Polyphenols EGCG and Theaflavin Inhibit the Activity of SARS-CoV-2 3CL-Protease In Vitro

Figure 6

EGCG auto-oxidation products (EAOPs) show the inhibitory effect on SARS-CoV-2 3CL protease. Auto-oxidation of EGCG was carried out to produce EAOPs for the indicated hours. EAOPs (10 μg/ml) were incubated with 3CL-protease, and the 3CL-protease activity was determined (top panel). “Con”, mock control. The mean and standard deviation are shown. ; NS, not significant. Time-dependent color changes of EAOPs were shown (bottom panel).

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