Associations of Interleukin-1β with H. pylori-Induced Gastric Atrophy and Syndrome of Dampness-Heat in the Spleen and Stomach in Subjects with H. pylori-Related Gastric Diseases

Table 4

Multinomial logistic regression in cascade stages of HPGD.

	GI vs. NOR		GA vs. GI		GPL vs. GA		GSD vs. GPL		GC vs. GSD
	RR (95% CI)		RR (95% CI)		RR (95% CI)		RR (95% CI)		RR (95% CI)
Age per 10 years	1.47 (1.03–2.06)	0.033	0.97 (0.75–1.26)	0.827	1.29 (1.00–1.68)	0.052	1.06 (0.72–1.57)	0.753	1.76 (1.08–2.86)	0.024
Gender
Female	Ref.	—	Ref.	—	Ref.	—	Ref.		Ref.
Male	2.19 (1.01–4.73)	0.046	0.73 (0.39–1.37)	0.333	1.14 (0.61–2.14)	0.609	1.83 (0.69–4.88)	0.228	1.30 (0.39–4.36)	0.673
H. pylori
Negative	Ref.	—	Ref.	—	Ref.	—	Ref.		Ref.
positive	2.89 (1.35–6.16)	0.006	5.51 (2.06–14.72)	0.001	0.79 (0.27–2.35)	0.678	0.65 (0.17–2.51)	0.527	2.25 (0.34–15.03)	0.401
IL-1B-511
CC	Ref.	—	Ref.	—	Ref.	—	Ref.		Ref.
CT	1.06 (0.42–2.77)	0.870	0.61 (0.28–1.29)	0.196	1.60 (0.75–3.39)	0.224	0.88 (0.30–2.57)	0.815	1.74 (0.44–6.83)	0.425
TT	1.61 (0.52–4.97)	0.409	0.66 (0.27–1.60)	0.362	1.42 (0.58–3.43)	0.442	0.28 (0.05–1.53)	0.142	4.61 (0.66–32.19)	0.124