Hepatoprotective Activity of BV-7310, a Proprietary Herbal Formulation of Phyllanthus niruri, Tephrosia purpurea, Boerhavia diffusa, and Andrographis paniculata, in Alcohol-Induced HepG2 Cells and Alcohol plus a Haloalkane, CCl4, Induced Liver Damage in Rats
Table 1
Blood chemistry of animals at the end of the study.
Groups
Total protein (g/dl)
Serum alanine transaminase ALT (IU/L)
Serum aspartate aminotransferase AST (IU/L)
Alkaline phosphatase ALP (IU/L)
Serum bilirubin (mg/dl)
Male rats
I
6.32 ± 0.31
44.86 ± 6.93
116.77 ± 11.11
155.13 ± 10.35
0.51 ± 0.05
II
6.23 ± 0.25
171.90 ± 74.37
242.80 ± 73.59
215.15 ± 62.02
0.87 ± 0.11
III
6.24 ± 0.30
69.27 ± 11.8
151.07 ± 36.21
138.65 ± 15.83
0.59 ± 0.05
IV
6.46 ± 0.24
66.01 ± 9.8
153.77 ± 31.05
130.13 ± 8.85
0.54 ± 0.13
Female rats
I
6.01 ± 0.27
40.92 ± 5.33
111.47 ± 12.99
118.27 ± 14.72
0.53 ± 0.06
II
6.03 ± 0.50
156.87 ± 26.13
352.05 ± 63.32
187.80 ± 27.83
0.87 ± 0.14
III
6.11 ± 0.07
49.24 ± 4.06
139.83 ± 26.21
139.48 ± 23.86
0.60 ± 0.08
IV
6.03 ± 0.11
68.08 ± 5.57
155.95 ± 26.53
137.10 ± 16.75
0.62 ± 0.12
value derived from values compared with group II (alcohol-treated group). Statistically significant .
