Research Article
Proliferation of Vascular Smooth Muscle Cells under ox-LDL Is Regulated by Alismatis rhizoma Decoction via InhibitingERK1/2 and miR-17∼92a Cluster Activation
Figure 6
Effects of AD and ERK1/2 inhibitor U0126 on the expression of cell-cycle regulatory proteins in ox-LDL-induced VSMCs. Western blot analysis was performed to determine the expression of cyclin D1, cyclin E, and p27, while β-actin served as a loading control. The graphs represented the relative expression of these proteins for three independent experiments. ox-LDL vs. control group; ox-LDL vs. control group; AD or U0126 vs. the ox-LDL group; AD or U0126 vs. the ox-LDL group.
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