Review Article

Acupuncture for the Postcholecystectomy Syndrome: A Systematic Review and Meta-Analysis

Table 4

Quality of evidence included RCTs by GRADE.

InterventionsIncluded RCTs (patients)Relative effect (95% CI)Quality assessmentQuality of evidence
Risk of biasInconsistencyIndirectnessImprecisionPublication bias

Reducing pain intensity
AT + CM3 (272)SMD 1.33 (−0.78 to 3.43)−1①−1②000Low
AT1 (60)SMD −0.21 (−0.72 to 0.30)000−1③0Moderate

POVN
AT + CM3 (312)RR 0.71 (0.55 to 0.92)−1①0000Moderate
AT2 (170)RR 0.82 (0.60 to 1.12)−1①0000Moderate
AT + TCM + CM1 (74)RR 0.50 (0.05 to 5.28)−1①00−1③−1④Very low

First defecation time
AT + CM3 (244)SMD −2.05 (−2.39 to −1.72)0−1②000Moderate
AT1 (60)SMD −1.64 (−2.24 to −1.05)000−1③0Moderate
AT + TCM + CM1 (387)SMD −1.03 (−1.26 to −0.79)−1①000−1④Low

First flatus time
AT + CM7 (648)SMD −2.66 (−3.82 to −1.50)−1①−1②000Low
AT1 (60)SMD −0.69 (−1.21 to −0.17)000−1③0Moderate
AT + TCM + CM2 (461)SMD −2.07 (−2.31 to −1.83)−1①000−1④Low

First bowel sounds time
AT + CM4 (402)SMD −2.85 (−3.15 to −2.55)−1①−1②000Low
AT + TCM + CM2 (461)SMD −2.91 (−3.19 to −2.64)−1①000−1④Low

Notes. ①Most information is from the moderate risk studies, and there are major limitations. ②The size and direction of the effect size, the overlap of the confidence interval is small, the value of the heterogeneity test is small, and the combined results of I2 value are large. ③The sample is insufficient. ④Few studies are included, and there may be a large publication bias.