Evidence-Based Complementary and Alternative Medicine

Review Article

STW1 and Its Versatile Pharmacological and Clinical Effects in Rheumatic Disorders: A Comprehensive Report

Table 4

Study parameters of randomized single- and double-blind studies with STW1.
Primary investigator [ref]MPCPMIMSTPExtPPatPSWRPFPRFIPSMNPATIComment
Meier [17]       xx     + 
Eberl et al. [18]              +Joint index, duration of morning stiffness
Schadler [19, 20]x   x    x    + 
Huber [21, 22] x              
Hahn and Hubner-Steiner [23, 24]xxx             
Speck et al. [25]xx x            
Bernhardt et al. [26]xxx             
Müller-Faßbender [27]a        a     + knee joint index
Schreckenberger [28]    xx         Only sum scores
Schreckenberger [29, 30]    xxx         
Schadler [19, 20]  x    x        
Schadler and Kalmbach [31]               Only lab. param.
Baumann et al. [32]x       xxxx    
Herzog et al. [33]x        x  x + 
Hawel et al. [34–36]x   x    x x   Including shoulder arm-syndrome
Michael and Sörensen [37]xx x            
Botzenhardt [38]   a           + strength of grip, sum score of 15 joints
Vajda and Kiss-Antal [39]a        aa  a  
MP = motor pain; CP = constant pain; MI = motor impairment, inhibition of active mobility; MS = morning stiffness; T = tenderness; PExt = pain during maximal extension against resistance; PPat = patient’s pain assessment; P = pain; SW = swelling; RP = rest pain; FPR = first pain after resting; FI = functional impairment; PSM = pain at start of movement; NP = nocturnal pain; ATI = additional tablet intake; x = ordinal scale; a = visual analogue scale.