Research Article

Endothelium-Independent Vasodilatory Effect of Sailuotong (SLT) on Rat Isolated Tail Artery

Figure 3

Effects of potassium channel blockers on SLT extract-induced relaxation on phenylephrine (1 μM)-preconstricted rat isolated tail artery. Tail arteries were preincubated with either vehicle control (○), tetrethyl-ammonium (TEA, a nonselective potassium channel blocker) (1 mM) (●), glibenclaminde (Glib, an ATP-sensitive potassium channel blocker) (3 μM) (■), or clotrimazole (KCa, a calcium-activated potassium channel blocker) (5 μM) (▲) for 30 minutes before construction of the concentration-response curve. Values are expressed as mean ± SEM (n = 5-6).