Endothelium-Independent Vasodilatory Effect of Sailuotong (SLT) on Rat Isolated Tail Artery

Figure 5

(a) Effect of the vehicle control (○), SLT extract (500 (●), 1000 (■), or 5000 (▲) μg/ml), or nifedipine (10 μM) (♦) on phenylephrine-induced vasoconstriction in rat isolated tail arteries. Values are expressed as mean ± SEM ( vs. control) (n = 5). (b) Isometric tension change of phenylephrine (10 μM)-induced vasoconstriction in rat isolated tail arteries with (closed bar) or without (open bar) the presence of the SLT extract (5000 μg/ml). Values are expressed as mean ± SEM () (n = 8). (c) Effect of the vehicle control (○) or SLT extract (500 (●), 1,000 (■), or 5,000 (▲) μg/ml) on potassium chloride (KCl) (80 mM)-induced vasoconstriction in rat isolated tail arteries. Values are expressed as mean ± SEM (; ; vs. control) (n = 3). (d) Isometric tension change of KCl (80 mM)-induced vasoconstriction in rat isolated tail arteries with (closed bar) or without (open bar) the presence of the SLT extract (5,000 μg/ml). Values are expressed as mean ± SEM () (n = 3).

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