Electroacupuncture Attenuates Inflammation after Ischemic Stroke by Inhibiting NF-κB-Mediated Activation of Microglia

Figure 4

Effects of electroacupuncture on the expression of CD11b in pMCAO rats. (a) Expression of CD11b in the cortical ischemic penumbra 2 h, 1 d, and 3 d after pMCAO, as determined by laser confocal scanning microscopy. Bar = 50 μm. (b) MFI of CD11b. The expression of CD11b in the model groups was increased after cerebral ischemia ( and versus the sham surgery group). Electroacupuncture decreased the expression of CD11b in pMCAO rats ( and versus the model group). (c) Expression of CD11b in the cortical ischemic penumbra 1 d after pMCAO. Fluorescently labeled microglia were green, and there were areas of the IP in which CD11b cells were obviously activated in the model group. In contrast to that in the model group, the expression of CD11b in the electroacupuncture group was reduced. Bar = 100 μm.

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