Acidic Phospholipase A2-Peptide Derivative Modulates Oxidative Status and Microstructural Reorganization of Scar Tissue after Cutaneous Injury

Table 1

Wound area (mm²) and the Wound Contraction Index (WCI) (%) in animals treated with different concentrations of LAPLA2.

Day	Area/Contraction	C	SS	L1 0.5%	L2 0.25%
0	Area (mm^2)	110.00 ± 0.00	100.00 ± 0.00	105.00 ± 0.00	108.00 ± 0.00
	WCI (%)	00.00 ± 00.00	00.00 ± 00.00	00.00 ± 00.00	00.00 ± 00.00
4	Area (mm^2)	76.66 ± 9.42	83.33 ± 9.42	60.00 ± 21.60	80.00 ± 8.16
	WCI (%)	30.30 ± 10.49	16.66 ± 11.54	42.85 ± 25.19	25.92 ± 9.25
8	Area (mm^2)	70.00 ± 16.32	53.33 ± 12.47	23.33 ± 4.71	46.66 ± 12.47
	WCI (%)	36.36 ± 18.1	46.66 ± 15.27	77.77 ± 5.49	56.79 ± 14.14
12	Area (mm^2)	20.00 ± 00.00	13.33 ± 4.71	6.66 ± 4.71	11.66 ± 2.35
	WCI (%)	81.81 ± 00.00	86.66 ± 5.77	93.65 ± 5.49	89.19 ± 2.67

C group: saline solution (0.9%), SS group: silver sulfadiazine (1%), L1 group: LAPLA2 (0.05%), L2 group: LAPLA2 (0.25%). Data are presented as mean ± SD. Statistical differences compared to the group C, and .