Research Article

Supplementation of L-Arginine, L-Glutamine, Vitamin C, Vitamin E, Folic Acid, and Green Tea Extract Enhances Serum Nitric Oxide Content and Antifatigue Activity in Mice

Figure 1

Effect of LVFG supplementation exercise performance. (a) Forelimb grip strength. (b) Swimming exercise performance: mice were subjected to an exhaustive swimming exercise with a load equivalent to 5% of the mouse’s body weight attached to its tail, and exercise performance test male ICR mice were pretreated with vehicle or 615, 1230, and 3075 mg/kg LVFG (1X, 2X, and 5X, respectively) before undergoing a grip strength test and swimming test 1 h after the final administered dose. (c) Effect of LVFG on serum nitric oxide (NO) at rest: all mice were sacrificed and examined for nitric oxide levels after the final treatment. Data is expressed as mean ± SEM for n = 8 mice in each group. One-way ANOVA was used for the analysis, and different letters (a, b) indicate significant difference at .