RNA-Seq Analysis of the Liver Transcriptome Reveals the Networks Regulating Treatment of Sitagliptin Phosphate plus Fuzhujiangtang Granule in the Zucker Diabetic Fatty Rats
Table 1
Measure of body weight, FBG, and RBG of rats in NC, DM, SP, FJG, and SP-FJG groups.
Group
1st week
2nd week
3rd week
4th week
5th week
6th week
Body weight (g)
NC
284.3 ± 11.82
309.3 ± 44.57
297.6 ± 11.78
310.1 ± 10.76
322.8 ± 9.93
316.2 ± 9.66
DM
331.2 ± 18.09
352.4 ± 13.07
363.15 ± 23.32
375.13 ± 29.89
374.4 ± 29.08
378.6 ± 52.48
SP
320.8 ± 16.6
342.37 ± 22.5
346.46 ± 14.33
344.4 ± 17.95
357.7 ± 21.14
343.94 ± 25.17
FJG
331.3 ± 18.05
337.8 ± 17.77
345.8 ± 19.28
353.1 ± 26.55
356.6 ± 22.71
342.8 ± 26.75
SP-FJG
341.6 ± 21.60
353.1 ± 16.86
354.9 ± 22.03
346.64 ± 21.3
344.5 ± 16.73
324.09 ± 18.95
FBG (mmol/L)
NC
3.71 ± 0.39
3.59 ± 0.21
3.43 ± 0.18
3.41 ± 0.17
4.03 ± 0.29
3.7 ± 0.39
DM
4.68 ± 0.93
5.6 ± 0.99
7.79 ± 1.79
8.38 ± 2.12
11.53 ± 2.63
12.65 ± 3.31
SP
4.64 ± 0.86
4.96 ± 0.86
5.68 ± 1.26
5.36 ± 0.92
5.43 ± 1
7.31 ± 2.49
FJG
4.55 ± 0.69
5.11 ± 0.63
6.45 ± 1.73
5.47 ± 1.29
6.12 ± 1.07
6.9 ± 0.77
SP-FJG
4.7 ± 0.51
4.8 ± 0.72
6.69 ± 2.45
5.32 ± 1.19
5.45 ± 1.27
7.44 ± 1.12
RBG (mmol/L)
NC
5.04 ± 0.26
4.21 ± 0.23
4.15 ± 0.24
3.66 ± 0.14
3.48 ± 0.27v
3.61 ± 0.12
DM
18.58 ± 3.24
20.07 ± 3.71
19.88 ± 2.8
22.25 ± 2.85
23.03 ± 4.85
24.84 ± 4.29
SP
17.6 ± 4.75
17.08 ± 3.8
18.75 ± 3.36
19.45 ± 3.54
17.06 ± 2.04
18.4 ± 2.31
FJG
19.08 ± 4.55
16.87 ± 3.2
18.2 ± 3.56
18.07 ± 4.3
17.08 ± 2.96
19.27 ± 2.25
SP-FJG
18.44 ± 4.24
16.34 ± 3.76
15.85 ± 4.17
16.92 ± 2.1
14.92 ± 4.9
16.65 ± 3.18
All values represent the means ± SD (n = 10). Significant difference with the DM group designated as . Significant difference with the DM group designated as . Significant difference with the SP group designated as . Significant difference with the SP group designated as .
