RNA-Seq Analysis of the Liver Transcriptome Reveals the Networks Regulating Treatment of Sitagliptin Phosphate plus Fuzhujiangtang Granule in the Zucker Diabetic Fatty Rats
Table 2
Measure of OGTT and ITT of rats in NC, DM, SP, FJG, and SP-FJG groups.
Group
Blood glucose (mmol/L)
AUC
0 min
30 min
60 min
120 min
OGTT
NC
3.72 ± 0.47
6.24 ± 2
4.46 ± 0.48
3.42 ± 0.37
9.11 ± 1.04
DM
11.24 ± 2.06
23.48 ± 3.37
27.04 ± 3.95
22.64 ± 5.73
46.15 ± 5.74
SP
8.4 ± 1.08
20.08 ± 1.63
21.56 ± 2.17
17.68 ± 2.02
37.15 ± 1.54
FJG
7.84 ± 1.39
21.1 ± 2.83
20.52 ± 2.15
17.94 ± 4.29
36.87 ± 2.77
SP-FJG
7.94 ± 1.43
17.98 ± 2.17
19.04 ± 3.1
14.62 ± 1.67
32.57 ± 3.15
ITT
NC
3.02 ± 0.17
1.88 ± 0.44
1.66 ± 0.41
2.04 ± 0.6
3.96 ± 0.45
DM
16.7 ± 2.77
12.34 ± 1.69
8.64 ± 1.21
10.46 ± 1.81
22.06 ± 2.17
SP
7.8 ± 0.66
4.68 ± 0.61
4.36 ± 0.85
5.3 ± 0.87
10.21 ± 1.02
FJG
10.1 ± 1.34
7.08 ± 0.83
6.26 ± 1.8
6.08 ± 0.63
13.8 ± 1.56
SP-FJG
9.76 ± 2.25
3.88 ± 0.42
4 ± 0.71
4.38 ± 0.64
9.57 ± 1.08
All values represent the means ± SD (n = 5). Significant difference with the DM group designated as . Significant difference with the DM group designated as . Significant difference with the SP group designated as . Significant difference with the SP group designated as .
