Evidence-Based Complementary and Alternative Medicine

Research Article

Exploring the Mechanism of Action Compound-Xueshuantong Capsule in Diabetic Retinopathy Treatment Based on Network Pharmacology

Biological process of Compound-Xueshuantong Capsule in diabetic retinopathy treatment.


ID	Description	Gene ID	Count

GO: 0004879	Nuclear receptor activity	PGR/ESR1/AR/PPARG/NR3C1/RXRB/AHR	7
GO: 0098531	Transcription factor activity, direct ligand regulated sequence-specific DNA binding	PGR/ESR1/AR/PPARG/NR3C1/RXRB/AHR	7
GO: 0003707	Steroid hormone receptor activity	PGR/NR3C2/ESR1/AR/PPARG/NR3C1/RXRB	7
GO: 0001228	Transcription activator activity, RNA polymerase II-specific	PGR/ESR1/AR/RELA/NR3C1/FOS/RXRB/HIF1A/NFE2L2/PARP1/IRF1	11
GO: 0097153	Cysteine-type endopeptidase activity involved in apoptotic process	CASP9/CASP3/CASP7/CASP1	4
GO: 0005496	Steroid binding	PGR/NR3C2/ESR1/AR/NR3C1/CAV1	6
GO: 0001085	RNA polymerase II transcription factor binding	ESR1/AR/PPARG/FOS/AHR/NFE2L2	6
GO: 0030331	Estrogen receptor binding	ESR1/PPARG/PCNA/PARP1	4
GO: 0001221	Transcription cofactor binding	ESR1/RELA/AHR/NFE2L2	4
GO: 0042826	Histone deacetylase binding	RELA/CCND1/MAPK8/HIF1A/PARP1	5
GO: 0001091	RNA polymerase II basal transcription factor binding	ESR1/AR/AHR	3
GO: 0001223	Transcription coactivator binding	ESR1/RELA/AHR	3
GO: 0005178	Integrin binding	EGFR/ICAM1/VCAM1/PRKCA/IGF2	5
GO: 0035257	Nuclear hormone receptor binding	ESR1/PPARG/PCNA/HIF1A/PARP1	5
GO: 0051117	ATPase binding	PGR/ESR1/AR/CAV1	4
GO: 0033613	Activating transcription factor binding	PPARG/RELA/FOS/NFE2L2	4
GO: 0035258	Steroid hormone receptor binding	ESR1/PPARG/PCNA/PARP1	4
GO: 0016504	Peptidase activator activity	APP/CAV1/CASP1	3
GO: 0051427	Hormone receptor binding	ESR1/PPARG/PCNA/HIF1A/PARP1	5
GO: 0042562	Hormone binding	ACHE/AR/EGFR/NR3C1	4