The Ethanol Extract of Avocado (Persea americana Mill. (Lauraceae)) Seeds Successfully Induces Implant Regression and Restores Ovarian Dynamic in a Rat Model of Endometriosis

Table 2

Effects of the ethanol extract of P. americana seeds on the number of antral follicles, luteinized unruptured follicles, and corpora lutea in rat ovaries.

Groups	Antral follicles	Corpora lutea	LUFs
[NORMAL]	15 ± 0.894	38.4 ± 2.785^µµµ	0.2 ± 0.2
[SHAM]	5.6 ± 1.029^µµµ	21 ± 2.588^µµµ	0.4 ± 0.244
[ENDO + DW]	1.6 ± 0.509^µµµ#	11.4 ± 1.568^µµµ##	4 ± 0.316^µµµ###
[ENDO + LTZ]	4.4 ± 0.509^µµµ	15 ± 1.516^µµµ	3.8 ± 0.583^µµµ###
[ENDO + EE12.5]	4 ± 0.707^µµµ	15.4 ± 1.288^µµµ	0.6 ± 0.244
[ENDO + EE25]	4.6 ± 0.748^µµµ	18.2 ± 1.2^µµµ	1.4 ± 0.4
[ENDO + EE50]	4.2 ± 0.583^µµµ	14.4 ± 2.111^µµµ	0.8 ± 0.374

Results are expressed as mean ± SEM, n = 5, versus [NORMAL]; , , and , versus [SHAM]; and versus [ENDO + DW]. SHAM: sham-operated animals; ENDO: animals with endometriosis; DW: distilled water; LTZ: letrozole; EE: ethanol extract of P. americana seeds; LUFs: luteinized unruptured follicles.