Bioactivities and Future Perspectives of Chaetoglobosins

Table 1

Summary of bioactive chaetoglobosins.

Number	Compounds	Activities	References
1	Chaetoglobosin A	Antitumor	[1, 9, 12–17]
		Antifungus	[1, 3, 18–20]
		Antibacterial	[8, 19, 21]
		Phytotoxicity	[12, 22]
		Nematicidal	[9, 23, 24]
		Fibrinolytic activity	[7]
2	19-O-Acetylchaetoglobosin A	Antitumor	[9]
		Nematicidal	[9]
3	20-Dihydrochaetoglobosin A	Antitumor	[12]
4	Chaetoglobosin B	Antitumor	[2, 14, 15, 18]
		Antifungus	[19]
		Antibacterial	[8, 19]
5	19-O-Acetylchaetoglobosin B	—	[25]
6	Chaetoglobosin C	Antitumor	[1, 2, 17, 26]
		Antifungal	[1, 19]
		Antibacterial	[27]
		Phytotoxicity	[12, 22]
7	Chaetoglobosin D	Antitumor	[2, 14, 15]
		Antifungal	[15, 18, 19]
		Antibacterial	[16]
8	19-O-Acetylchaetoglobosin D	—	[25]
9	Chaetoglobosin E	Antitumor	[1, 14, 16, 17, 26, 28]
		Antifungal	[1, 18]
		Phytotoxicity	[12]
10	Chaetoglobosin F	Antitumor	[1, 2, 12, 16, 17, 26]
		Phytotoxicity	[1, 12]
		Immunosuppressive property	[29]
11	Chaetoglobosin Fa	Antitumor	[12]
		Phytotoxicity	[12]
12	Chaetoglobosin F (ex)	Antitumor	[12, 17, 26]
		Phytotoxicity	[12]
		Antiinflammatory property	[30]
13	Chaetoglobosin G	Antitumor	[1, 2, 17, 18, 28]
		Antifungal	[1, 31]
		Antibacterial	[31]
14	Chaetoglobosin J	Antitumor	[15, 32]
15	Chaetoglobosin K	Antitumor	[18, 33–39]
		Antifungal	[40, 41]
16	Chaetoglobosin M	Antifungal	[4, 41]
17	Chaetoglobosin N	—	[4]
18	Chaetoglobosin O	Antitumor	[14, 42]
19	Chaetoglobosin P	—	[43]
20	Chaetoglobosin Q	Antitumor	[15]
21	Chaetoglobosin R	Antifungal	[18, 20]
22	Chaetoglobosin S	—	[31]
23	Chaetoglobosin T	Antitumor	[15]
		Antifungal	[20]
		Antibacterial	[20, 27]
24	Chaetoglobosin U	Antitumor	[16]
25	Chaetoglobosins V	Antitumor	[2, 12, 14, 17, 32, 44]
		Antifungal	[31]
		Antibacterial	[27, 31]
		Phytotoxicity	[12]
26	Chaetoglobosin V (b)	Antitumor	[12]
		Antifungal	[31]
		Antibacterial	[31]
		Phytotoxicity	[12]
27	Chaetoglobosin W	Antitumor	[17]
28	Chaetoglobosin X	Antitumor	[45]
		Antifungal	[45]
29	Chaetoglobosin Y	Antitumor	[28]
30	Chaetoglobosin Z	Antitumor	[14]
31	Chaetoglobosin-510	Antitumor	[46]
32	Chaetoglobosin-540	Antitumor	[46]
33	Chaetoglobosin-542	Antitumor	[46]
34	Isochaetoglobosin D	Antitumor	[2, 28]
35	Isochaetoglobosin J	—	[47]
36	Yamchaetoglobosin A	Antitumor	[10]
		Anticoagulant activity	[10]
37	Penochalasin A	Antitumor	[16, 48]
38	Penochalasin B	Antitumor	[48]
39	Penochalasin C	Antitumor	[26, 48]
40	Penochalasin D	Antitumor	[42]
41	Penochalasin E	Antitumor	[42]
42	Penochalasin F	Antitumor	[42]
43	Penochalasin G	Antitumor	[42]
44	Penochalasin H	Antitumor	[42]
45	Penochalasin I	Antitumor	[1]
		Antifungal	[1]
		Antibacterial	[27]
46	Penochalasin J	Antitumor	[1]
		Antifungal	[1]
47	Penochalasin K	Antitumor	[49]
		Antifungal	[49]
48	Prochaetoglobosin I	Antitumor	[15]
		Antibacterial	[27]
49	Isprochaetoglobosin I	—	[46]
50	Prochaetoglobosin II	Antitumor	[6, 15]
51	Prochaetoglobosin III	Antitumor	[2]
		Antiamebic	[24]
52	Prochaetoglobosin IIIed	Antitumor	[2]
53	Prochaetoglobosin IV	—	[47]
54	Trimethylated chaetoglobosin	—	[4]
55	Armochaetoglasins A	Antitumor	[50]
		Antibacterial	[27]
56	Armochaetoglasin B	Antitumor	[32, 51]
		Antibacterial	[27]
57	Armochaetoglasin C	Antitumor	[51]
		Antibacterial	[27]
58	Armochaetoglasin D	Antitumor	[51]
59	Armochaetoglasin E	Antitumor	[51]
60	Armochaetoglasin F	—	[51]
61	Armochaetoglasin G	Antitumor	[51]
62	Armochaetoglasin H	Antitumor	[51]
63	Armochaetoglasin I	Antitumor	[1, 51]
		Antifungal	[1]
64	Armochaetoglasin J	Antitumor	[51]
65	Armochaetoglasin K	Anti-HIV I	[11]
66	Armochaetoglasin L	Anti-HIV I	[11]
67	Armochaetoglasin M	Anti-HIV I	[11]
68	Armochaetoglasin N	Anti-HIV I	[11]
69	Armochaetoglasin O	Anti-HIV I	[11]
70	Armochaetoglasin P	Anti-HIV I	[11]
71	Armochaetoglasin Q	Anti-HIV I	[11]
72	Armochaetoglasin R	Anti-HIV I	[11]
73	Armochaetoglasin S	Antitumor	[50]
74	7-O-Acetylarmochaetoglobin S	Antitumor	[50]
75	Armochaetoglasin T	Antitumor	[50]
76	Armochaetoglasin U	Antitumor	[50]
77	Armochaetoglasin V	Antitumor	[50]
78	Armochaetoglasin W	Antitumor	[50]
79	Armochaetoglasin X	Antitumor	[50]
80	Armochaetoglasin Y	Antitumor	[50]
		Antibacterial	[27]
81	Armochaetoglasin Z	Antitumor	[50]
82	Aureochaeglobosin A	Antitumor	[52]
83	Aureochaeglobosin B	Antitumor	[52]
84	Aureochaeglobosin C	Antitumor	[52]
85	Oxichaetoglobosin A	Antitumor	[53]
		Immunomodulatory activity	[53]
86	Oxichaetoglobosin B	Antitumor	[53]
		Immunomodulatory activity	[53]
87	Oxichaetoglobosin C	Antitumor	[53]
		Immunomodulatory activity	[53]
88	Oxichaetoglobosin D	Antitumor	[53]
		Immunomodulatory activity	[53]
89	Oxichaetoglobosin E	Antitumor	[53]
		Immunomodulatory activity	[53]
90	Oxichaetoglobosin F	Antitumor	[53]
		Immunomodulatory activity	[53]
91	Oxichaetoglobosin G	Antitumor	[53]
		Immunomodulatory activity	[53]
92	Oxichaetoglobosin H	Antitumor	[53]
		Immunomodulatory activity	[53]
93	Oxichaetoglobosin I	Antitumor	[53]
		Immunomodulatory activity	[53]