Electroacupuncture Alleviates Pain-Related Emotion by Upregulating the Expression of NPS and Its Receptor NPSR in the Anterior Cingulate Cortex and Hypothalamus
Effects of EA stimulation on anxiety-like behaviors induced by the C-CPA model on day 6. (a) Time spent in the open arms in each group. (b) Distance traveled in the open arms in each group. (c) Total distance traveled in the EOM apparatus in each group. (d) Representative pictures of animals’ movement traces on the EOM apparatus in each group (Quadrants 1 and 4 represent the closed arms, while 2 and 3 the open arms). Sixteen rats in each group. and , C-CPA, EA, and sham EA vs. control; and , EA vs. C-CPA; , EA vs. sham EA.