Research Article
In Vitro and In Vivo Wound Healing and Anti-Inflammatory Activities of Babassu Oil (Attalea speciosa Mart. Ex Spreng., Arecaceae)
Table 3
Nitric oxide (NO) and cytokines released by LPS-stimulated macrophages.
| | | [ ] (µg/mL) | NO (µM) | INF-γ (pg/mL) | TNF-α (pg/mL) | IL-2 (pg/mL) | IL-6 (pg/mL) |
| | PBS | — | 0.03 ± 0.01 | <0.5 | <0.9 | 496.0 ± 110.4 | <1.4 | | LPS | — | 1.15 ± 0.19 | 980.4 ± 38.6 | <0.9 | 516.4 ± 105.7 | 584.4 ± 18.4 | | Babassu oil | 3.12 | 0.31 ± 0.12 | 2200.1 ± 82.8 | 107.7 ± 19.2 | 245.0 ± 133.9 | 1286.1 ± 25.9 | | | 6.25 | 0.28 ± 0.10 | 2214.2 ± 28.5 | <0.9 | 310.5 ± 90.6 | 1266.3 ± 8.6 | | | 12.5 | 0.29 ± 0.09 | 1925.6 ± 7.1 | 26.3 ± 45.6 | 578.9 ± 110.9 | 1197.4 ± 11.8 | | DEXA | 10 | 0.72 ± 0.12 | <0.5 | <0.9 | 619.2 ± 157.0 | 7.3 ± 1.3 | | L-NAME | 25 | 0.31 ± 0.05 | — | — | — | — |
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Data were analyzed by ANOVA followed by the Bonferroni posttest, considering significant values of when compared with group LPS. —: not tested. |
