Research Article
A Comprehensive Toxicological Assessment of Fulvic Acid
Table 5
Results of the bacterial reverse mutation test of FA.
| Drugs | Concentration (μg per plate) | TA97 | TA98 | TA100 | TA102 | +S9 | −S9 | +S9 | −S9 | +S9 | −S9 | −S9 | +S9 |
| FA | 1.6 | 156.0± 9.6 | 145.7 ± 9.3 | 42.7 ± 4.7 | 38.7 ± 4.5 | 165.7 ± 9.1 | 155.7 ± 6.1 | 284.3 ± 10.6 | 294.0 ± 8.2 | 8 | 135.0 ± 8.5 | 148.0 ± 10.5 | 41.7 ± 2.5 | 41.3 ± 3.5 | 167.3 ± 8.0 | 157.0 ± 7.5 | 276.0 ± 6.6 | 284.3 ± 10.0 | 40 | 153.3 ± 6.5 | 135.3 ± 8.0 | 37.3 ± 3.5 | 42.7 ± 4.2 | 174.7 ± 10.7 | 175.7 ± 12.6 | 277.3 ± 9.1 | 275.7 ± 9.9 | 200 | 154.3 ± 8.5 | 137.0 ± 9.0 | 39.3 ± 4.0 | 37.3 ± 4.5 | 165.7 ± 8.6 | 172.7 ± 10.6 | 275.3 ± 8.5 | 306.0 ± 11.1 | 1,000 | 163.0 ± 10.5 | 143.3 ± 10.1 | 34.0 ± 3.1 | 36.7 ± 3.1 | 159.3 ± 11.7 | 154.7 ± 6.5 | 283.3 ± 10.7 | 304.0 ± 10.0 |
| H2O | — | 143.7 ± 8.7 | 134.0 ± 7.0 | 39.0 ± 4.0 | 38.3 ± 4.2 | 174.3 ± 8.0 | 155.0 ± 12.1 | 267.0 ± 7.5 | 286.7 ± 11.1 | DMSO | — | 155.3 ± 7.1 | 128.0 ± 9.2 | 35.3 ± 3.8 | 38.0 ± 4.6 | 155.0 ± 7.5 | 166.7 ± 13.1 | 264.0 ± 7.0 | 257.0 ± 14.5 | 2-Aminofluoren | 10 | 898.3 ± 68.1 | — | 580.0 ± 28.2 | — | 920.0 ± 64.4 | — | 1329.0 ± 41.6 | — | Sodium azid | 1.5 | — | — | — | — | — | 1034.7 ± 57.9# | — | — | p-dimethyl amino benzene diazo sodium sulfonate | 50 | — | 553.7 ± 31.1 | — | 559.3 ± 15.4 | — | — | — | 1380.7 ± 28.0 |
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FA, fulvic acid; —, no data; , compared to the corresponding control group; , compared to the DMSO control group. |