Evaluation of Antidiabetic Activity of the Leaf Latex of Aloe pulcherrima Gilbert and Sebsebe (Aloaceae)
Table 4
The effect of the leaf latex of Aloe pulcherrima on glucose level in diabetic mice.
Groups
Blood glucose level (mg/dl)
Pretreatment
Week one
Week two
10 ml/kg vehicle NC
89.17 ± 1.56
88.86 ± 1.89
90.56 ± 1.35
10 ml/kg vehicle DC
258.47 ± 1.39
262.62 ± 1.09
263.75 ± 4.23
5 mg/kg glibenclamide
260.56 ± 3.37
240.17 ± 2.50 a3b1
233.33 ± 1.89 a3b1
200 mg/kg·LL
259.33 ± 2.43
248.47 ± 2.44 a1c1
241.27 ± 1.96a2c1
400 mg/kg·LL
261.49 ± 2.98
247.28 ± 2.99 a2
237.15 ± 4.09a3
600 mg/kg·LL
259.89 ± 2.50
245.45 ± 2.50a3b1
234.21 ± 0.72a3
The result is expressed as mean ± standard error of the mean, n = 6; acompared to diabetic control; bto 200 mg/kg; cto 5 mg/kg glibenclamide; 1;2;3. DC, diabetic control; LL, leaf latex; NC, normal control.