Research Article

Evaluation of Antidiabetic Activity of the Leaf Latex of Aloe pulcherrima Gilbert and Sebsebe (Aloaceae)

Table 4

The effect of the leaf latex of Aloe pulcherrima on glucose level in diabetic mice.

GroupsBlood glucose level (mg/dl)
PretreatmentWeek oneWeek two

10 ml/kg vehicle NC89.17 ± 1.5688.86 ± 1.8990.56 ± 1.35
10 ml/kg vehicle DC258.47 ± 1.39262.62 ± 1.09263.75 ± 4.23
5 mg/kg glibenclamide260.56 ± 3.37240.17 ± 2.50 a3b1233.33 ± 1.89 a3b1
200 mg/kg·LL259.33 ± 2.43248.47 ± 2.44 a1c1241.27 ± 1.96a2c1
400 mg/kg·LL261.49 ± 2.98247.28 ± 2.99 a2237.15 ± 4.09a3
600 mg/kg·LL259.89 ± 2.50245.45 ± 2.50a3b1234.21 ± 0.72a3

The result is expressed as mean ± standard error of the mean, n = 6; acompared to diabetic control; bto 200 mg/kg; cto 5 mg/kg glibenclamide; 1; 2; 3. DC, diabetic control; LL, leaf latex; NC, normal control.