Suppression of Dynamical Network Biomarker Signals at the Predisease State (Mibyou) before Metabolic Syndrome in Mice by a Traditional Japanese Medicine (Kampo Formula) Bofutsushosan

Table 1

Composition of BTS extract granules for ethical use (TJ-62) employed in the present study.

Crude drug name	Amount (g)
JP aluminum silicate hydrate with silicon dioxide	3.0
JP scutellaria root	2.0
JP glycyrrhiza	2.0
JP platycodon root	2.0
JP gypsum	2.0
JP atractylodes rhizome	2.0
JP rhubarb	1.5
JP schizonepeta spike	1.2
JP gardenia fruit	1.2
JP peony root	1.2
JP cnidium rhizome	1.2
JP Japanese angelica root	1.2
JP mentha herb	1.2
JP saposhnikovia root	1.2
JP Ephedra herb	1.2
JP forsythia fruit	1.2
JP anhydrous mirabilitum	0.7
JP ginger	0.3

A total of 4.5 g of a dried extract was obtained from the above described mixed crude drugs. By adding inactive ingredients (JP light anhydrous silicic acid, JP magnesium stearate, and JP lactose hydrate), 7.5 g of the extract granules was prepared. JP: Japanese pharmacopoeia.