Research Article

Comparatively Evaluating the Role of Herb Pairs Containing Angelicae Sinensis Radix in Xin-Sheng-Hua Granule by Withdrawal Analysis

Table 2

Amounts (mg) of the 21 compounds in XSHG and six samples of decomposed recipes (n = 6).

AnalyteSamples (mg, n = 6)
XSHGObs.aSamThe.bDYObs.aDCObs.aDTObs.aDHObs.aDJObs.aDZObs.a

1208.01 ± 8.45208.01 ± 8.45n.d.191.10 ± 6.87196.70 ± 4.52182.30 ± 8.73187.95 ± 4.32183.92 ± 7.95
22148.92 ± 103.412148.92 ± 103.41n.d.1820.32 ± 67.632130.15 ± 91.831924.15 ± 48.822087.40 ± 84.162050.64 ± 84.67
338.78 ± 4.3019.53 ± 1.0221.08 ± 1.71#n.d.17.66 ± 1.2619.95 ± 1.4619.70 ± 1.1119.32 ± 1.20
4507.14 ± 27.22507.14 ± 27.22374.82 ± 24.23419.03 ± 14.53517.11 ± 19.44n.d.453.51 ± 23.24467.63 ± 22.91
5100.93 ± 5.0756.16 ± 3.0662.07 ± 2.14##n.d.50.73 ± 2.7339.30 ± 2.1448.78 ± 2.4251.68 ± 1.73
6430.58 ± 36.53430.58 ± 36.53358.24 ± 23.02342.14 ± 18.58n.d.377.47 ± 15.62456.07 ± 26.64##390.51 ± 15.81
754.34 ± 3.6025.56 ± 1.3924.18 ± 1.51n.d.22.49 ± 1.3528.62 ± 1.47##23.31 ± 1.3421.84 ± 1.17
895.45 ± 4.0395.45 ± 4.03n.d.66.95 ± 4.1099.45 ± 6.2580.20 ± 4.0386.72 ± 5.3969.60 ± 3.66
973.55 ± 3.3573.55 ± 3.3575.77 ± 4.0665.99 ± 2.9491.00 ± 2.79##81.04 ± 2.68##76.15 ± 2.19n.d.
10267.52 ± 20.7682.98 ± 5.7574.16 ± 3.52n.d.99.20 ± 8.67##99.87 ± 7.65##91.91 ± 7.95##85.35 ± 6.04
1121.93 ± 1.4321.93 ± 1.4315.27 ± 1.3116.51 ± 1.5819.44 ± 1.2418.68 ± 1.40n.d.16.45 ± 1.07
122.17 ± 0.172.17 ± 0.171.62 ± 0.111.82 ± 0.123.48 ± 0.22##2.77 ± 0.12##2.20 ± 0.16n.d.
13134.92 ± 7.0760.39 ± 2.2674.46 ± 2.47##n.d.70.98 ± 3.34##59.66 ± 1.8263.81 ± 1.5765.80 ± 1.81#
1473.81 ± 6.3626.46 ± 1.7936.44 ± 2.55##n.d.34.83 ± 1.05##30.17 ± 1.67##30.87 ± 0.97##32.57 ± 1.72##
152.51 ± 0.242.51 ± 0.242.62 ± 0.223.18 ± 0.14##3.30 ± 0.24##2.75 ± 0.222.41 ± 0.16n.d.
16430.17 ± 20.84430.17 ± 20.84423.49 ± 22.98460.62 ± 21.44##474.48 ± 28.63##395.46 ± 15.28397.73 ± 19.17n.d.
1747.87 ± 2.6947.87 ± 2.6928.97 ± 2.0039.33 ± 2.6049.91 ± 3.0233.66 ± 2.62n.d.39.09 ± 2.24
18437.86 ± 32.07173.97 ± 10.72187.92 ± 17.68n.d.206.68 ± 12.24##172.80 ± 7.15172.44 ± 11.35162.31 ± 11.21
19572.17 ± 33.48199.26 ± 9.15152.60 ± 6.28n.d.228.98 ± 14.30##195.75 ± 13.48175.37 ± 6.65166.62 ± 7.41
2036.96 ± 3.6120.07 ± 0.5611.25 ± 0.62n.d.17.47 ± 0.8811.79 ± 0.6312.77 ± 0.7510.68 ± 0.79
211.43 ± 0.101.43 ± 0.100.84 ± 0.0591.26 ± 0.091.78 ± 0.12##1.52 ± 0.12n.d.1.31 ± 0.08

n.d. = not detectable; and (the observed amount decreased in comparison with its theory amount); and (the observed amount increased in comparison with its theory amount). aObs., the observed amount of each compound in different samples. bThe theorized amount of each compound in the samples of decomposed recipes. Except for aromatic acids and phthalides, the theorized amounts of other compounds in the decomposed recipes were the observed amounts of the analytes in XSHG accordingly; for aromatic acids and phthalides, the theorized content could be calculated: AmountThe. = Proportionality coefficient of CX × Amount of the analyte in XSHG. 1, trigonelline; 2, stachydrine hydrochloride; 3, protocatechuic acid; 4, hydroxysafflor yellow A; 5, chlorogenic acid; 6, amygdalin; 7, caffeic acid; 8, leonurine hydrochloride; 9, liquiritin; 10, ferulic acid; 11, zingerone; 12, isoliquiritoside; 13, senkyunolide I; 14, senkyunolide H; 15, liquiritigenin; 16, glycyrrhizic acid; 17, 6-gingerol; 18, senkyunolide A; 19, ligustilide; 20, butylidenephthalide; 21, 6-shogaol.